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Library Synthesis
Over the past decade we have acquired considerable experience in making over a hundred solid and solution phase library sets for our clients.
Our library synthesis services include:
Diverse Library = > 200-2000 compounds
Quantity =10-25mg
Purity range > 80%
Focused Library = 10-200 compounds
Quantity =25-100 mg
Purity range > 95%
We can develop these libraries either in solid phase or solution phase
Solution Phase
Types of Chemistry:
- Amide formation
- Sulphonamide formation
- Reductive amination
- Suzuki coupling
- Aromatic nucleophilic substitution
- Knovenagel condensation
- Thiazoles
- O - and N – alkylations
Solid Phase
Types of Resins used:
- Wang, Kaiser oxime, SALSA,
- Sasrine, MB-CHO
Types of Chemistry:
- Amide formation
- Sulphonamide formation
- Reductive amination
- Aromatic nucleophilic substitution
Shipment:
Complete analysis of final compound is carried out and shipped in Amber vials or in Micronics plates , along with analytical reports such as LCMS HPLC,NMR (if needed ) for verification.
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