Robust and Scalable Chemical Development for Your Molecule
From route scouting for complex APIs and method development, to large-scale cGMP manufacturing, we are your dedicated partner for accelerating chemical process development.
Trusted to deliver critical programs for global innovators
Syngene has built credibility in chemical product development through experienced scientists, cutting-edge infrastructure, robust quality systems, and a proven track record. Noteworthy achievements include developing the world’s first drug for a rare paediatric disease and delivering significant cost savings for clients.
Commitment to innovation, compliance, and sustainability—plus being a publicly listed company—solidifies Syngene’s position as a trusted global CDMO.
Core Expertise in Chemical Development
Syngene’s workforce includes process chemists, engineers, and analytical scientists with expertise across synthetic organic chemistry, process chemistry, analytical chemistry, process safety, and engineering. Supported by supply chain, QC, and QA experts, we provide a complete ecosystem for reliable chemical development.
API Development & Manufacturing
End-to-End API Realization
Key Value Drivers:
Robust synthesis route design ensures cost efficiency and quality
Wide and safe API scale-up (including HPAPIs) in state-of-the-art containment
Advanced platforms like Flow Chemistry improve efficiency, safety, and speed
High-Potency API (HPAPI) Services
Expertise in High-Potency Molecules
Key Value Drivers:
Dedicated cGMP-compliant facility for cytostatic compounds
(OELs down to 0.01 μg/m³)
Facility includes isolators, diverse reactors, and downstream equipment
Batch capacity up to 30 kg, scalable from development to commercial
Lifecycle support from containment/analysis to safe production and regulatory compliance
Advanced Chemistry Platforms
Solving Complex Synthetic Challenges
Key Value Drivers:
Flow Chemistry:
High efficiency, safety, reproducibility, green chemistry benefits
Complex & Hazardous Chemistry:
Safe handling with isolators, protocols, and track record in chiral inductions, organometallics, and high-pressure reactions
Catalysis:
Broad catalytic processes (metal-catalysed C–C bond formations, asymmetric chiral inductions, hydrogenation, oxidation, epoxidation, methylation)
Performance & Specialty Chemicals
Beyond Pharmaceuticals
Key Value Drivers:
Development of, specialty polymers, and performance chemicals
Scale-up from grams to multi-ton production
Example: Specialty polymer membrane developed for a clean energy client, outperforming benchmarks
Infrastructure & Quality
Our Commitment to Excellence
Key Value Drivers:
Ready to Build a Robust Chemical Process?
Partner with a team that has the expertise, infrastructure, and track record to ensure your project’s success.