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I am delighted to share that one of our clients, Panbela, recently announced the issuance of a new patent in Japan for a novel process for producing SBP-101, a pancreatic cancer drug. The press release stated: "This patent, developed in collaboration with Syngene International Ltd., an integrated research, development, and manufacturing services company, claims a novel process with a reduced number of synthetic steps from seventeen to six to produce SBP-101,a lead investigational product. The patent is valid till 2039".
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Season's Greetings for a happy and prosperous new year.
Syngene continues to invest in technical capabilities, operational excellence, and infrastructure.
I am delighted to share that Syngene recently purchased 17 acres of land in Genome Valley, Hyderabad, in addition to our existing research campus housing ~900 scientists. Over the next few years, we plan to invest up to US$95 Mn to build world-class research laboratories primarily focused on drug discovery to further strengthen our commitment to our clients.
Read Press Release
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In other news, Syngene received four Gold awards for four SQDECC Kaizen case studies from the Chapter Convention of Quality Concepts organized by the Quality Circle Forum of India. SQDECC, which stands for Safety, Quality, Delivery, Engagement, Compliance, and Cost, is Syngene's Lean daily management tool for ensuring operational excellence.
We also won the Golden Peacock Award for Risk Management in the pharmaceutical category (national), given under the seal of the Institute of Directors, India, for having met the overall requirements of the Golden Peacock Excellence Model
As before, we have a store of interesting articles for you.
Happy reading!
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| Kenneth J. Barr, Ph.D. |
Senior Vice President, Discovery Services
Syngene International Ltd. |
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| In Vitro & Genetic Toxicology - AMES Test |
| Syngene's Genetic Toxicology suite has undergone a significant upgrade. Using a state-of-the-art laboratory, our team of expert toxicologists has streamlined the process to deliver AMES test reports on the same day the test is completed. This efficiency level has been made possible by one of India's first installations of the highly sensitive Sorcerer colony counter equipped with Cyto Study Manager software, which complies with GLP and 21 CFR regulations. Explore our genetic toxicology capabilities, which enable comprehensive genotoxicity evaluations from initial screening to IND submission. |
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| Syngene adds new Compound Management facility in Hyderabad |
| Syngene is proud to announce the inauguration of its Central Compound Management facility in Hyderabad. This state-of-the-art facility features Hamilton robotic storage systems and offers secure, centralized storage, automated sample tracking, precision temperature control, and streamlined data management. |
| As a result, our compound management team can seamlessly oversee compound storage, profiling, and distribution - reducing operational errors and project delays. |
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| Powering up antibody-drug conjugates with PROTACs |
| Antibody Drug Conjugates (ADCs) are a rapidly expanding domain within targeted cancer treatments, merging antibodies with cell-killing molecules. Effective synthesis hinges on harmonizing these elements. Our white paper delves into ADC preparation methods, the potential for heightened target precision using PROTAC-equipped antibodies, and the vital role of contract research development and manufacturing organizations (CRDMOs) in supporting continued innovation for this class of compounds. |
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| Leveraging High Throughput Screening services to accelerate drug discovery |
Employed primarily for target identification, high-throughput screening (HTS) services have since evolved to encompass HT-ADME screening, toxicology studies, and the discovery of optimal excipients and formulations. This blog delves into the latest developments in this space, including the growing dependence on third-party HTS service providers. It also throws light on the criteria for selecting the right partner for outsourced HTS services.
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© 2024, Syngene International Ltd.
Biocon Park, SEZ, Bommasandra Industrial Area - Phase-IV Bangalore 560099 India
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