Putting Science to Work

Process Hazard Analysis

Syngene follows a systematic approach for the hazard identification and risk assessment of the processes prior to the scale up. This exercise is done at the development stage and the process is subjected to a process hazard assessment checklist followed by brainstorming sessions. Based on these sessions, the requirement of thermo chemical evaluation by DSC or RC1 is identified and evaluated. Up on thermo chemical evaluation, the process is modified further to make it a safer process.

The various aspects considered for the process hazard identification and risk assessment are:
  • Basic chemistry
  • MSDS of chemicals involved
  • Reaction/addition sequence
  • Facility
  • Utilities
  • Personnel
  • Thermo chemical calculations

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