• Small Molecules
    • Large Molecules
    • Other Drug Modalities
    • SynVent Integrated Drug Discovery
      • SynVent Integrated Drug Discovery

        SynVent is Syngene’s platform for fully integrated therapeutic discovery and development across large and small molecules. 

    • Industries
    • Dedicated Centers
      • Dedicated Centers

        Our Dedicated Centers offer dedicated multi-disciplinary scientific teams, support personnel, and a tailormade ring-fenced and fire-walled infrastructure as per client specifications to support their  R&D  goals

    • Center for Advanced Protein Studies (CAPS)
      • Center for Advanced Protein Studies (CAPS)

        Centre for Advanced Protein Studies [CAPS] is a state-of-the-art advanced national facility located in the Syngene campus, Bangalore.

  • Careers

In Vitro and Genetic Toxicology

Assessing the potential genotoxicity of compounds through in vitro studies

Syngene’s genetic toxicology department helps clients characterize the potential genotoxicity of compounds from screening to investigational new drug (IND) submission. Our experienced scientists work in state-of-the-art facilities to provide current and comprehensive studies as per the guidelines of the Organization for Economic Co-operation and Development (OECD). 

Our team of experienced analytical and bioanalytical specialists, toxicologists, and statisticians has been supporting genetic toxicology studies since 2010. Over the last two years, we completed more than 300 genetic toxicology studies for our partners.


We offer a range of in vitro toxicology studies that are more predictive of human response, enable a quicker turnaround time, provide stand-alone data for specific endpoints, and help screen and rank chemicals by studying specific targets in cells and tissues.

Our offerings include standard genotoxicity studies as well as in vitro cytotoxicity assays conducted using the neutral red uptake (NRU) method that helps screen the cytotoxic potential of compounds. We recently included a range of in vitro-based test offerings, such as phototoxicity tests using Bagg Albino inbred mouse strain (BALB/c) 3T3 method, skin irritation and corrosion tests using reconstructed human epidermis (RHE), and eye irritation tests using reconstructed human cornea-like epithelium (RhCE) test methods. 

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