• Small Molecules
      • Discovery
    • Large Molecules
    • Other Drug Modalities
    • SynVent Integrated Drug Discovery
      • SynVent Integrated Drug Discovery

        SynVent is Syngene’s platform for fully integrated therapeutic discovery and development across large and small molecules. 

    • Industries
    • Emerging Biopharma
      • Emerging Biopharma

        Emerging biopharma work at the forefront of science, often venturing into disease areas where little or no real-world data exists to work with or regulatory frameworks to work within.

    • Dedicated Centers
      • Dedicated Centers

        Our Dedicated Centers offer dedicated multi-disciplinary scientific teams, support personnel, and a tailormade ring-fenced and fire-walled infrastructure as per client specifications to support their  R&D  goals

    • Center for Advanced Protein Studies (CAPS)
      • Center for Advanced Protein Studies (CAPS)

        Centre for Advanced Protein Studies [CAPS] is a state-of-the-art advanced national facility located in the Syngene campus, Bangalore.

  • Careers


AI-enhanced relay-based drug discovery for optimizing Design-Make-Test-Analyze (DMTA) cycle

SynVantage is Syngene’s platform that enables a continuous and seamless transition between different stages of the Design-Make-Test-Analyze (DMTA) cycle in drug discovery.
The process ensures a relay-based changeover between scientists and other support functions who may be working in shifts in the laboratories at any stage in the drug discovery cycle.

Relay-based approach

In a relay-based model, the ownership for a discovery program lies collectively with a team of scientists. They work collaboratively in a round-the-clock shift system with a just-in-time approach, thereby eliminating inefficiencies and waste. For example, in a small molecule discovery program based on the relay-based model, a team of chemists would work in a coordinated, tandem manner on each chemical reaction step within a synthetic scheme – reagent procurement to reaction set-up, monitoring, and workup, purification, and characterization.

The 24/7 or 24/5 relay model can be configured to cover all three work shifts on a working day with efficient planning and operations. Further, a team leader assigned to this model would ensure seamless handover between two scientists in two different shifts.

Accelerating drug discovery cycle with SynVantage

We believe that our 24/7 or 24/5 relay-based discovery can significantly reduce early discovery timelines by 12 to 18 months, depending on the type of project being handled.
Supporting SynVantage in this task are AI-based predictive algorithms that rapidly and accurately understand the patterns and molecular changes required to predict the optimal compound.  This in turn, would result in:

  • Optimal utilization of resources
  • Faster response to emerging needs for therapeutic discovery
  • Faster time-to-market in bringing new therapies to patients in need

SynVantage can be used across Syngene’s drug discovery offerings of Chemistry, Biology, Safety Assessment, and Computational & Data Sciences. All the support functions at Syngene like procurement and stores, purification, analysis, EHS, administration, IT, HR, and operations have also been enabled to complement the relay model.

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