Essential In vivo Safety – Tox studies to move your molecule from Target to IND successfully
Learn about Syngene’s expertise in Safety/Tox studies that allows us to guide you through the various requirements leading to successful IND submission.
DMPK strategies to avoid drug development mistakes early
Learn the DMPK strategies that have helped Syngene scientists avoid drug development mistakes early while driving cost-effective, reproducible, high-quality data for clients.
How Syngene developed a multi-drug combination, antiparasitic drug for dogs for a leading Animal Health company
Learn how Syngene developed an antiparasitic tablet for dogs containing multiple APIs (one of which is a very low dose) in just six months.
Structure-Based Optimization and Discovery of M3258, a Specific Inhibitor of the Immunoproteasome Subunit LMP7 (β5i)
Publication: Journal of Medicinal Chemistry
Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series
Publication: Journal of Medicinal Chemistry
Solvent-Dependent Photophysics and Reactivity of Monomeric and Dimeric 4-Amino-1,8-Naphthalimides
Publication: The Journal of Physical Chemistry A
Synthetic platform for mono-functionalised tridentate macrocycles as key precursors of mechanically-linked macromolecular systems
Publication: Organic Chemistry Frontiers
US FDA approved drugs from 2015-June 2020-A perspective
Publication: Journal of Medicinal Chemistry
Selective recruitment of γδ T cells by a bispecific antibody for the treatment of acute myeloid leukemia
Publication: Leukemia
A novel reactor configuration for continuous virus inactivation
Publication: Biochemical Engineering Journal