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        SynVent is Syngene’s platform for fully integrated therapeutic discovery and development across large and small molecules. 

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      • Center for Advanced Protein Studies (CAPS)

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Secure and traceable compound storage for faster drug discovery

Syngene offers a comprehensive, state-of-the-art, centralized Compound Management facility for supporting drug discovery projects of its customers, partners, and industry peers through automated storage, efficient sample tracking, data accuracy, and access to sample inventory.

The Central Compound Management (CCM) System would enable our customers to manage the storage, profiling, and distribution of compounds seamlessly, thereby improving efficiency and reducing the technical/operational errors and time lags in projects. The tools have sufficient flexibility and scalability to adapt to new demands. New screening strategies can also be enabled to accelerate DMTA cycle of the projects. This would be achieved via centralized storage, automated sample tracking, precise temperature-controlled environments, and the latest data management software. Established in collaboration with Hamilton (Switzerland), the facility provides a seamless link between Chemistry and Biology operations.

Compound Management services at Syngene 

Features of Syngene’s Compound Management System

  • Fully automated, state-of-the-art instrumentation for managing compounds and supporting screening to enable teams across the globe to work seamlessly and collaborate in real-time
  • 24 X7 monitoring of laboratory temperature and humidity to ensure compound integrity
  • Individually barcoded tubes and containers to enable full inventory tracking across different functions and stages of the discovery continuum
  • Support for the entire process flow from compound registration to managing stock preparations, assay-ready plate (ARP) generation, distribution, and inventory management
  • End-to-end integration with the Titian Mosaic application system ensures a secure web-based interface for our partners to fast-track the flow of their compounds to relevant projects. It also allows them to check the inventory of their stored compounds at any given time
  • Long-term storage at a competitive pricing

 

Why Syngene 

  • Maintenance of sample integrity across different processes
  • Fast sample accessibility through cherry-picking
  • Quality and error-free handling through barcodes
  • Traceability and reliable inventory data through Mosaic
  • Compound stocks and process efficiency
  • 3S solution ‘Synthesis-Storage-Screening’ for your compounds providing end-to-end quality solutions

Infrastructure highlights

  • Solid storage capacity: 70,000 compounds
  • Liquid storage capacity: > 0.3 million tubes in high-density racks with additional scope for expansion by 3X

Instrumentation features

  • Automated Compound Storage System:
    • Hamilton Verso at +4°C
    • Hamilton Verso at -20°C
  • Liquid Handling Systems
    • Fluent from Tecan integrated with capper/decapper from Hamilton and plate seal
    • ECHO 650

Syngene’s Compound Management facility is fully operational, supporting all types of small molecule projects, fostering efficient compound sharing, reducing retrieval time, minimizing the risk of compound degradation, and, in the process, accelerating drug discovery and development programs 

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