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Toxicology Formulations

Toxicology Formulations

Developing drug formulations for toxicology studies

Syngene’s experts are well-versed in developing formulations to support preclinical studies and GLP toxicology studies for peroral, parenteral and other routes of administration.

Capabilities

Our experts develop suspension and solution formulations using various solubilization approaches that include pH adjustment, co-solvents, surfactants, and cyclodextrins. We apply enabling approaches such as nanosuspension, solid dispersions, and micro/ nano-emulsions to improve the bioavailability of drugs. We also assess formulations for in vitro precipitation potential and short-term stability. The team selects excipients for the formulation based on the route of administration, animal species, duration of the study, and acceptability for human use in Phase 1 clinical study.

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