Developing, optimizing, and scaling processes to support manufacturing of formulations
Syngene’s Formulation Development center supports process development and scale-up using state-of-the-art infrastructure and equipment. Our experts are proficient in scaling various manufacturing processes over a broad scale range (0.1 to 100 kilograms for oral solids).
Our process development capabilities include direct blending and compression process to produce tablets. We are well-versed with wet, dry and top spray granulation methods, extrusion and spheronization. We also provide Wurster coating for mini tablets and pellets.
Our experts apply the principles of quality by design (QbD) to assess the risk of formulation and process parameters and help identify high-risk factors that could potentially impact the critical quality attributes of a product. Using experimental design techniques, our experts then identify and optimize these process parameters to positively impact the quality of products.