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Archives

Developing a green synthesis process for a growth promoter drug for animals

Learn how Syngene developed a green synthesis process for a growth promoter drug for an animal health company that reduced the cE factor and PMI value by 80% while achieving high yield and cost-efficiency.

Reducing variability in gene expression: Bottlenecks and Solutions

Explore challenges in reducing the variability in gene expression in traditional cell line development (CLD) and the power of the transposon system to address these inefficiencies.

Enabling a four-fold increase in titer for mAb manufacturing using Syngene’s platform process

Learn how Syngene’s platform approach to mAb manufacturing helped a biopharma company achieve a four-fold increase in titer in less than a year, resulting in improved efficiency and reduced costs.

IND-enabling safety tox studies for FDA submission in just 9 months

Learn how Syngene supported a pharma company in completing IND-enabling safety tox studies for their lead compound for treating painful neuropathies in less than nine months.

Developing a unique hybridoma platform for manufacturing mAb cocktail formulations

Learn how Syngene developed a unique hybridoma platform for manufacturing mAb cocktail formulations for use in reagent kits designed to activate and expand human T cells for immunotherapy in patients.

Harnessing the immune system for cancer cell-therapy

Explore the top challenges in developing CAR-T therapy for treating cancer and how leading CRO-CDMO Syngene supports clients in bringing this therapy to patients faster.

Development of a Scalable Process for the Synthesis of Cyclopropyl-Methyl-Proline with Complex Stereochemistry: A Key Building Block of Factor D Inhibitors

Publication: ACS Publications

Quantifying a biomarker in mice brain for treating mood and anxiety disorders

A robust LC-MS-based quantitative method developed at Syngene to measure biomarker 2-AG in mice brain tissues for treating mood and anxiety disorders.

SynWeaveTM: Integrating Speed, Titer and Quality webinar

BWC0977, a broad-spectrum antibacterial clinical candidate to treat multidrug resistant infections

Publication: Nature Communications

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