US FDA approved drugs from 2015-June 2020-A perspective
Publication: Journal of Medicinal Chemistry
Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series
Publication: Journal of Medicinal Chemistry
Structure-Based Optimization and Discovery of M3258, a Specific Inhibitor of the Immunoproteasome Subunit LMP7 (β5i)
Publication: Journal of Medicinal Chemistry
TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity
Publication: mAbs
Systematic mutational analysis reveals an essential role of N275 in IgE stability
Publication: Biotechnology and Bioengineering, Wiley
Development of a Scalable Process for the Synthesis of Cyclopropyl-Methyl-Proline with Complex Stereochemistry: A Key Building Block of Factor D Inhibitors
Publication: ACS Publications
BWC0977, a broad-spectrum antibacterial clinical candidate to treat multidrug resistant infections
Publication: Nature Communications
Application of Ion-Exchange Chromatographic Technique using Resins to Prepare the Salts of Polar Unstable Prodrugs and New Chemical Entities (NCEs)
Publication: Journal of Pharmaceutical Sciences
GLP-1 Drugs Now Stand at the Centre of a Multi-Disease Treatment Revolution
Publication: Pharmaceutical Technology Focus
Bile acid modulators in discovery: Identifying cholestasis candidates with the best chance of success
Publication: Pharmaceutical Technology Focus